A ray of hope for microbiological diagnostics – molecular probes for the detection of pathogens in clinical samples

Diagnostic detection of bacterial pathogens in clinical samples is an important prerequisite for successful antimicrobial treatment. A team from the Helmholtz Centre for Infection Research (HZI) in Braunschweig, led by Prof. Mark Brönstrup, the German Center for Infection Research (DZIF) and Tel Aviv University, Israel, has now developed molecular probes that can detect different bacterial species with high sensitivity. Bacterial cells activate the probes and cause them to glow. This signal enables pathogen detection directly in clinical samples. The results were recently published in the scientific journal “Angewandte Chemie”.

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